Patients can present with skin eruptions that are localized to a small area or covering their body. Diagnosing skin lesions and rashes are a fundamental part of dermatologic care. However, an accurate diagnosis is based on a thorough assessment and differential diagnosis. Dermatology clinicians must be able to differentiate life-threathing skin diseases, from infections, and hypersensitivity reaction. A organized approach based on primary morphology is the key!